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CL Chun, S Eisenstat, S Dormady… - Digestive diseases and …, 2011 - Springer
A 38-year-old non-smoking male with a history of juvenile polyposis syndrome (JPS) and adenocarcinoma
of the colon presented for a second opinion for a bleeding rectal mass and difficulty swallowing
both solids and liquids. The patient had been in his usual state of good health until he ...
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WA van Hattem, D Langeveld… - … American Journal of …, 2011 - journals.lww.com
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D Calva, FS Dahdaleh, G Woodfield… - Nucleic Acids …, 2011 - Oxford Univ Press
Inactivation of SMAD4 has been linked to several cancers and germline mutations cause juvenile
polyposis (JP). We set out to identify the promoter(s) of SMAD4, evaluate their activity in cell lines
and define possible transcription factor binding sites (TFBS). 5′-rapid amplification of ...
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F Schwenter, F Ratjen, T Berk… - Journal of Pediatric …, 2011 - journals.lww.com
Juvenile Polyposis Syndrome (JPS) is an autosomal dominant condition characterized by multiple
juvenile polyps in the gastrointestinal tract with a lifetime cancer risk of 39%. A subset of JPS
patients have mutations in the SMAD4 gene. Recently, a combined syndrome of ...
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B Hood, S Bigler, P Bishop, H Liu… - Clinical …, 2011 - cpj.sagepub.com
Colonic polyps are a common finding in children, rep- resenting one of the most common causes
of rectal bleeding in this age group.1 Historically, the vast major- ity of childhood polyps are
solitary, located in the distal colon, and are histologically classified as juvenile pol- yps ...
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