A Troisi, G Frazzetto, V Carola… - Social …, 2011 - Taylor & Francis A large body of evidence links altered opioid signaling with changes in social behavior in animals. However, few studies have attempted to determine whether similar links exist in humans. Here we investigate whether a common polymorphism (A118G) in the mu-opioid ... Cited by 2 - Related articles - All 5 versions
[HTML] from ukpmc.ac.ukL Milan-Lobo… - Journal of Pharmacology and Experimental …, 2011 - ASPET Heteromerization of opioid receptors has been shown to alter opioid receptor pharmacology. However, how receptor heteromerization affects the processes of endocytosis and postendocytic sorting has not been closely examined. This question is of particular relevance for ... Related articles - All 4 versions
[PDF] from yale.eduR Ray, K Ruparel, A Newberg… - Proceedings of the …, 2011 - National Acad Sciences Evidence points to the endogenous opioid system, and the mu-opioid receptor (MOR) in particular, in mediating the rewarding effects of drugs of abuse, including nicotine. A single nucleotide polymorphism (SNP) in the human MOR gene (OPRM1 A118G) has been shown to alter ... Related articles - All 4 versions
M Zastrow - The Opiate Receptors, 2011 - Springer Membrane trafficking mechanisms play a fundamental role in controlling the number and subcellular distribution of opioid receptors in target neurons. The membrane trafficking of opioid receptors is remarkably specific and highly regulated, and there has been considerable progress in ... Related articles - All 2 versions
KM Raehal, CL Schmid, CE Groer… - Pharmacological Reviews, 2011 - ASPET Opioids are the most effective analgesic drugs for the management of moderate or severe pain, yet their clinical use is often limited because of the onset of adverse side effects. Drugs in this class produce most of their physiological effects through activation of the μ opioid ...
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