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[PDF] Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies

[PDF] from 124.42.15.59PA Wachholz, JN Francis, MR Jacobson, I Kimber… - 2011 - 124.42.15.59
Background: Grass pollen immunotherapy for allergic rhinitis is a disease-modifying treatment
that results in long-term clinical tolerance lasting years after treatment discontinuation. Active
treatment is associated with generation of inhibitory grass pollen–specific IgG antibodies ...
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Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies

LK James, MH Shamji, SM Walker… - Journal of Allergy and …, 2011 - Elsevier
We conducted a 4-year study in which patients who had moderate-to-severe allergic rhinitis underwent
a randomized, double-blind, placebo-controlled discontinuation of subcutaneous grass pollen
immunotherapy. All subjects received grass pollen immunotherapy injections for 2 years ...
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Contamination with recombinant IFN accounts for the unexpected stimulatory properties of commonly used IFN‐blocking antibodies

HP Moll, H Freudenthaler, A Zommer… - European journal of …, 2011 - Wiley Online Library
... Technical comment. Contamination with recombinant IFN accounts for the unexpected
stimulatory properties of commonly used IFN-blocking antibodies. Herwig P. Moll 1,† ,;
Harald Freudenthaler 1,† ,; Anna Zommer 1 ,; Elisabeth ...
All 4 versions

Transient congenital hypothyroidism due to thyroid-stimulating hormone receptor blocking antibodies: a case series

C Evans, JW Gregory, J Barton… - Annals of Clinical …, 2011 - acb.rsmjournals.com
We describe seven infants with transient congenital hypothyroidism (CH) due to maternal
thyroid-stimulating hormone receptor (TSH-R) blocking antibodies (TRAb) identified over three
decades of newborn screening for CH in Wales, UK that represents a minimum incidence ...
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The role of IgG antibodies in allergy and immunotherapy

R Aalberse - Allergy, 2011 - Wiley Online Library
... A second hypothesis is that IgG 4 antibodies act as blocking antibodies. This classical
explanation states ... activation of mast cells. Blocking antibodies are thought to neutralize
allergen so it no longer activates IgE-sensitized mast cells. ...
Related articles - All 3 versions

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