推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-54106218，021-33363733

chinasupport@letpub.com

登录 注册 新注册优惠

An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis

A Innocenzi, L Latella, G Messina, M Simonatto… - EMBO reports, 2011 - nature.com
Despite having distinct expression patterns and phenotypes in mutant mice, the myogenic regulatory
factors Myf5 and MyoD have been considered to be functionally equivalent. Here, we report that
these factors have a different response to DNA damage, due to the presence in MyoD ...
All 3 versions

The biotransformation of tamoxifen by human vytochrome P450 enzymes leads to the production of potentially genotoxic metabolites

L Notley, KH Crewe… - ASCEPT Annual …, 2011 - espace.library.uq.edu.au
... The biotransformation of tamoxifen by human vytochrome P450 enzymes leads to the production
of potentially genotoxic metabolites. ... The biotransformation of tamoxifen by human vytochrome
P450 enzymes leads to the production of potentially genotoxic metabolites. ...
Cached - All 3 versions

The Central Nervous System-Restricted Transcription Factor Olig2 Opposes p53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma

S Mehta, E Huillard, S Kesari, CL Maire… - Cancer Cell, 2011 - Elsevier
High-grade gliomas are notoriously insensitive to radiation and genotoxic drugs.
Paradoxically, the p53 gene is structurally intact in the majority of these tumors. Resistance to
genotoxic modalities in p53-positive gliomas is generally attributed to attenuation of p53 ...
All 2 versions

Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces transgene-specific immune tolerance with low genotoxic risk

J Matrai, A Cantore, C Bartholomae, A Annoni… - Hepatology, 2011 - lirias.kuleuven.be
... ITEM METADATA RECORD. Title: Hepatocyte-targeted expression by integrase-
defective lentiviral vectors induces transgene-specific immune tolerance with low
genotoxic risk. Authors: Matrai, Janka × Cantore, A Bartholomae ...
Cached

NF-κB Induction of the SUMO Protease SENP2: A Negative Feedback Loop to Attenuate Cell Survival Response to Genotoxic Stress.

MH Lee, AM Mabb, GB Gill, ET Yeh… - Molecular cell, 2011 - ncbi.nlm.nih.gov
Activation of NF-κB, pivotal for immunity and oncogenesis, is tightly controlled by multiple feedback
mechanisms. In response to DNA damage, SUMOylation of NEMO (NF-κB essential
modulator) is critical for NF-κB activation; however, the SUMO proteases and feedback ...

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海分公司    网站备案号：沪ICP备10217908号-1    沪公网安备号：31010402006960

增值电信业务经营许可证：沪B2-20211595

礼翰商务信息咨询（上海）有限公司      办公地址：上海市徐汇区漕溪北路88号圣爱大厦1803室

United States: Tel: 1-781-202-9968 Address: 400 5th Ave, Suite 530, Waltham, Massachusetts 02451