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Methods of using conjugated toxin peptide therapeutic agents

JK Sullivan, JG McGivern, LP Miranda… - US Patent …, 2011 - Google Patents
Page 1. inn iiiiiii hi mi mi iiii iiiijii iiiiijiii urn inn mi mi mi (12) United States Patent Sullivan et al.
(io) Patent No.: (45) Date of Patent: US 7,910,102 B2 *Mar. 22, 2011 (54) METHODS OF USING
CONJUGATED TOXIN PEPTIDE THERAPEUTIC AGENTS (75) Inventors: (73) Assignee ...
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TADB: a web-based resource for Type 2 toxin–antitoxin loci in bacteria and archaea

[HTML] from nih.govY Shao, EM Harrison, D Bi, C Tai, X He… - Nucleic Acids …, 2011 - Oxford Univ Press
... This second toxin, Gura_2467, contains a RES domain (COG5654), which contains three highly
conserved polar groups (arginine, glutamate and serine) that could form an active site. Its matching
antitoxin, Gura_2468, contains an Xre family HTH (helix-turn-helix) domain ...
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Treatment of metastatic colon cancer with b-subunit of shiga toxin

ON Kovbasnjuk… - US Patent 7,875,586, 2011 - Google Patents
... In further embodiments, the methods comprise administer- ing the B-subunit of Shiga toxin in
conjunction with other cancer therapies, including radiation and chemotherapy. ... Page 11. US
7,875, ,586 B2 3 to the rest of the cells from leading edge, bar—10 urn. FIG. ...
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Toxin detection method

K Ohishi, T Baba, K Hiramatsu… - US Patent 7,947,808, 2011 - Google Patents
... (io) Patent No.: (45) Date of Patent: US 7,947,808 B2 May 24, 2011 TOXIN DETECTION METHOD
Inventors ... 477-495, 1968).* V. Finck-Barbancon et al., "Improvedpurification of leukocidin from
Staphylococcus aureus and toxin distribution among hospital strains", Res. Microbiol. ...
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Clostridial toxin derivatives able to modify peripheral sensory afferent functions

KA Foster, MJ Duggan… - US Patent 7,892,560, 2011 - Google Patents
... US 7,892, ,560 B2 1 CLOSTRIDIAL TOXIN DERIVATIVES ABLE TO MODIFY PERIPHERAL
SENSORY AFFERENT FUNCTIONS CROSS-REFERENCE TO RELATED ... been classified
histologically; the cell bodies fall into two classes: A-type are large (60-120 urn in diameter ...
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