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An animal model of schizophrenia based on chronic LSD administration: Old idea, new results

D Marona-Lewicka, CD Nichols… - Neuropharmacology, 2011 - Elsevier
... We did notice, however, that LSD90-trained rats emitted a significantly higher number of lever
presses during training ... of animals to validate whether observed behavioral changes after
prolonged LSD administration resemble core symptoms of schizophrenia by measuring ...
All 2 versions

Modeling Motivational Deficits in Mouse Models of Schizophrenia: Behavior Analysis as a Guide for Neuroscience

RD Ward, EH Simpson, ER Kandel… - Behavioural Processes, 2011 - Elsevier
... Distortions in timing are observed in many patients with schizophrenia (eg, Clausen, 1950; Densen,
1977; Johnson & Petzel, 1971; Lhamon & ... is also evidenced by the decreased number of rewards
earned, and the decreased number of lever presses emitted by D2OE mice. ...
All 2 versions

Reality monitoring and its association with social functioning in schizophrenia

M Divilbiss, A McCleery, JM Aakre, JP Seghers… - Psychiatry research, 2011 - Elsevier
... reality monitoring, is the ability to discriminate the sources of information present in short-term
memory, such as emitted speech versus ... As with other types of source monitoring tasks, individuals
with schizophrenia have a difficult time making this differentiation ([Brunelin et al ...
All 4 versions

Group II mGluR agonist LY354740 and NAAG peptidase inhibitor effects on prepulse inhibition in PCP and d-amphetamine models of schizophrenia

CP Profaci, KA Krolikowski, RT Olszewski… - Psychopharmacology, 2011 - Springer
... Our model of NAAG peptidase inhibition- mediated reduction in schizophrenia-like behaviors
in animal models is based on activation of group II mGluRs by elevated NAAG levels (Neale et
al. ... Each prepulse lasted for 40 ms and was emitted 100 ms before the 2-ms startle. ...
Related articles - All 2 versions

Asymmetric alternation of the hemodynamic response at the prefrontal cortex in patients with schizophrenia during electroconvulsive therapy: A near infrared …

Y Fujita, M Takebayashi, K Hisaoka, M Tsuchioka… - Brain Research, 2011 - Elsevier
... performed 2) the score of the HAM-D was 7 or less in patients with mood disorders 3) the reduction
in the PANSS total score from pre-ECT was at least 50 % in the patients with schizophrenia. ... The
NIRO-200 utilizes near-infrared light emitted at three different wavelengths (typ. ...

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