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Hyaluronan as an immune regulator in human diseases

D Jiang, J Liang… - Physiological Reviews, 2011 - Am Physiological Soc
... Hyal2-deficient mice showed that murine HYAL2 has a physiological activity in ... verbascose,
planteose, and neomycin showed comparable inhibition on all hyaluronidases, thereby
possessing ... higher activity than that of the widely accepted hyaluronidase inhibitor apigenin (384 ...
Cited by 10 - Related articles - All 2 versions

Autodisplay of catalytically active human hyaluronidase hPH-20 and testing of enzyme inhibitors

A Kaeßler, S Olgen… - European Journal of Pharmaceutical …, 2011 - Elsevier
... Moreover, they could be helpful in elucidating the physiological function of hPH-20 ... All other
compounds were tested in assays using either bovine testes hyaluronidase (BTH) or ... Jedrzejas
2006) (figure 1). As a solution, recombinantly expressed human hyaluronidases could be ...
Cited by 4 - Related articles - All 3 versions

The Role of Hyaluronan and Hyaluronan Binding Proteins in Lung Pathobiology

FE Lennon… - American Journal of Physiology- …, 2011 - Am Physiological Soc
... doi:10.1152/ajplung.00071.2010 Copyright © 2011 by the American Physiological Society. ... Page
8. In addition to the enzymatic activity of hyaluronidases, HA can be degraded to low ... use of the
hyaluronidase inhibitor Vcpal (53). One could also speculate that the action of ...
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Inhibitory Effect of a Hot Water Extract of Coffee “Silverskin” on Hyaluronidase

M FURUSAWA, Y NARITA, K IWAI… - Bioscience, …, 2011 - J-STAGE
... is disposed of as industrial waste, although it is known that CS has antioxidative and prebiotic
effects as physiological functions.1 ... effect of a CS extract (CS-ext) on hyaluronidase and attempted
to determine the component functioning as a hyaluronidase inhibitor by fractionating ...
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Design of benzimidazole-and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase

S Braun, A Botzki, S Salmen, C Textor… - European Journal of …, 2011 - Elsevier
... HA is degraded by hyaluronidases, a class of enzymes with two main families, the eukaryotic
hyaluronoglucosaminidases ... 4-(3-Phenyl-1H-indol-2-yl)phenol inhibited bovine testes
hyaluronidase (IC 50 107 μM ... 3 shows that the inhibitor 5 binds in the cleft formed by the α-domain ...

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