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PA Grenier… - Diseases of the Heart and Chest, Including …, 2011 - Springer
... Asthma is a chronic inflammatory condition responsible for airway hyperresponsiveness to ... Over
time, this inflam- matory disorder induces structural changes in airways (fi- brosis, smooth-muscle
hypertrophia and hyperplasia, and neovessel formation), which lead to ...
E Dejonckheere, RE Vandenbroucke… - Cytokine & Growth Factor …, 2011 - Elsevier
... Besides degrading collagen, MMP8 can also modulate numerous inflammatory mediators. Second,
lung disorders are associated with a high degree of oxidative stress, and MMP8 is highly ... MMP8
was proven to play an essential role in both acute and chronic lung disorders. ...
Cited by 1 - Related articles - All 3 versions
A Sekiyama, Y Gon, M Terakado… - American Journal of …, 2011 - Am Thoracic Soc
... Nihon University School of Medicine, Tokyo, Japan 1 Asthma is a chronic inflammatory disorder
of the airway. Glucocorticoids (GCs) are by far the most effective anti-inflammatory therapy for
asthma. Epithelial barrier damage is a cardinal feature of chronic asthma. ...
All 3 versions
[PDF] from lonzabio.comS Damian, A Deighan, M Smithhisler… - Resource, 2011 - lonzabio.com
... Current drug targets of both diseases include certain enzymes or re- ceptors which are known
to modulate key cells involved in regulating pathogenic immunity and inflammatory responses. ...
Donors Diagnosed with Asthma or Chronic Obstructive Pulmonary Disorder (COPD) ...
S Borensztajn, H von der Thusen… - Current …, 2011 - ingentaconnect.com
... to play an essential role in idiopathic pulmonary fibrosis (IPF), whereas the role of PARs in other
chronic pulmonary disorders like COPD ... while PAR-1 expression is strongly upregulated in
macrophages and fibroblasts in fibroproliferative and inflammatory foci of ...
Related articles - All 2 versions

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