R Maehr, EO Mazzoni, DA Melton… - Mechanisms of …, 2011 - Elsevier Wnt signaling has been implicated in many developmental processes, but its role in early endoderm development is not well understood. Wnt signaling is active in posterior endoderm as early as E7.5. Genetic and chemical activation show that the Wnt pathway acts directly on ...
GM Keller… - US Patent 20,110,212,061, 2011 - freepatentsonline.com The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy. The present invention further ... Cached
S Brown, A Teo, S Pauklin, N Hannan… - STEM CELLS, 2011 - Wiley Online Library Author contributions: SB: Conception and design, Collection and/or assembly of data, Data analysis and interpretation; AT: Collection and/or assembly of data; SP: Collection and/or assembly of data; NH: Collection and/or assembly of data; CH-H C.: Collection and/or assembly of ... Related articles - All 2 versions
[HTML] from cshlp.orgAKK Teo, SJ Arnold, MWB Trotter… - Genes & …, 2011 - genesdev.cshlp.org Understanding the molecular mechanisms controlling early cell fate decisions in mammals is a major objective toward the development of robust methods for the differentiation of human pluripotent stem cells into clinically relevant cell types. Here, we used human embryonic ... Cited by 5 - Related articles - All 3 versions
FW Sand, A Hornblad, JK Johansson, C Loren… - Developmental …, 2011 - Elsevier Endoderm development is dependent on inductive signals from different structures in close vicinity, including the notochord, lateral plate mesoderm and endothelial cells. Recently, we demonstrated that a functional vascular system is necessary for proper pancreas development, and that ... Cited by 1 - Related articles - All 2 versions
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