E Willems, S Spiering, H Davidovics… - Circulation …, 2011 - ncbi.nlm.nih.gov Rationale: Human embryonic stem cells can form cardiomyocytes when cultured under differentiation conditions. Although the initiating step of mesoderm formation is well characterized, the subsequent steps that enrich for cardiac lineages are poorly understood and limit the yield of ... All 2 versions
GM Keller… - US Patent 20,110,212,061, 2011 - freepatentsonline.com The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy. The present invention further ... Cached
SY Lee, SK Lim, SW Cha, J Yoon, SH Lee… - Differentiation, 2011 - Elsevier In early vertebrate development, mesoderm induction is a crucial event regulated by several factors including the activin, BMP and FGF signaling pathways. While the requirement of FGF in Nodal/activin-induced mesoderm formation has been reported, the fate of the tissue ...
RH Row, JL Maītre, BL Martin, P Stockinger… - Developmental …, 2011 - Elsevier The process of gastrulation is highly conserved across vertebrates on both the genetic and morphological levels, despite great variety in embryonic shape and speed of development. This mechanism spatially separates the germ layers and establishes the organizational foundation for ... All 2 versions
B Bénazéraf, P François, N Denans… - Biologie aujourd' …, 2011 - ncbi.nlm.nih.gov Vertebrates are characterized by an elongated antero-posterior (AP) body axis. This particular shape arises during embryogenesis by mophogenetic events leading to elongation. Although elongation mechanisms that lead to the formation of the anterior part of the body are well ...
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