S Jacquemont, A Reymond, F Zufferey, L Harewood… - Nature, 2011 - ncbi.nlm.nih.gov Both obesity and being underweight have been associated with increased mortality. Underweight, defined as a body mass index (BMI) ≤ 18.5 kg per m(2) in adults and ≤ -2 standard deviations from the mean in children, is the main sign of a series of heterogeneous ...
M Zernicka-Goetz, C Patrat, I Okamoto, D Thépot… - Human …, 2011 - ESHRE A crucial question in mammalian development is how cells of the early embryo differentiate into distinct cell types. These cell fate decisions are taken when cells undertake waves of asymmetric divisions, which generate one daughter cell on the inside and one on the outside of the ...
E Larschan, EP Bishop, PV Kharchenko, LJ Core… - Nature, 2011 - nature.com The evolution of sex chromosomes has resulted in numerous species in which females inherit two X chromosomes but males have a single X, thus requiring dosage compensation. MSL (Male-specific lethal) complex increases transcription on the single X chromosome of ... Cited by 4 - Related articles - All 5 versions
A Kegel, H Betts-Lindroos, T Kanno, K Jeppsson… - Nature, 2011 - nature.com During chromosome duplication the parental DNA molecule becomes overwound, or positively supercoiled, in the region ahead of the advancing replication fork. To allow fork progression, this superhelical tension has to be removed by topoisomerases, which operate by ... Cited by 2 - Related articles - All 5 versions
[PDF] from uni-graz.atI Okamoto, C Patrat, D Thépot, N Peynot, P Fauque… - Nature, 2011 - nature.com X-chromosome inactivation (XCI) in female mammals allows dosage compensation for X-linked gene products between the sexes 1 . The developmental regulation of this process has been extensively investigated in mice, where the X chromosome of paternal origin (Xp) is ... Cited by 10 - Related articles - All 8 versions
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