BE Black, LE Jansen, DR Foltz… - Cold Spring Harbor …, 2011 - ncbi.nlm.nih.gov The key to understanding centromere identity is likely to lie in the chromatin containing the histone H3 variant CENP-A. CENP-A is the prime candidate to carry the epigenetic information that specifies the chromosomal location of the centromere in nearly all eukaryotic species, raising ... Related articles - All 3 versions
BE Black… - Cell, 2011 - Elsevier Centromeres direct chromosome inheritance, but in multicellular organisms their positions on chromosomes are primarily specified epigenetically rather than by a DNA sequence. The major candidate for the epigenetic mark is chromatin assembled with the histone H3 variant ... Cited by 5 - Related articles - All 4 versions
E Boyarchuk, R Montes de Oca… - Current Opinion in Cell …, 2011 - Elsevier Classical heterochromatin chromosomal landmarks, such as centromeres and telomeres, are characterized by specific chromatin signatures. Among these, the incorporation of histone variants has recently emerged as an important feature. Using the centromere as a paradigm, we ... Related articles - All 2 versions
Z Zhou, H Feng, BR Zhou, R Ghirlando, K Hu… - Nature, 2011 - nature.com The centromere is a unique chromosomal locus that ensures accurate segregation of chromosomes during cell division by directing the assembly of a multiprotein complex, the kinetochore 1 . The centromere is marked by a conserved variant of conventional histone H3 termed CenH3 ... Cited by 7 - Related articles - All 5 versions
[HTML] from nih.govUS Cho… - Proceedings of the National …, 2011 - National Acad Sciences A specialized nucleosome is a component of all eukaryotic kinetochores. The core of this nucleosome contains a centromere-specific histone, CENP-A (the Cse4 gene product in budding yeast), instead of the usual H3. Assembly of a centromeric nucleosome depends on a specific ... Cited by 2 - Related articles - All 4 versions
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