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C Li, N Narkbunnam, RJ Samulski, A Asokan… - Gene Therapy, 2011 - nature.com
Recombinant adeno-associated virus (rAAV) is a promising gene delivery vector and has recently
been used in patients with hemophilia. One limitation of AAV application is that most humans
have experienced wild-type AAV serotype 2 exposure, which frequently generates ...
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JM Wilson, G Gao, MR Alvira… - US Patent …, 2011 - Google Patents
■PQPIGEPPAGPSGLGSGTMAAGG ■PQPIGEPPAGPSGLGSGTMAAGG ■ASTGASNDNHYFGY
ASTGASNDNHYFGY TSTGASNDNHYFGY ■ASTGASNDNHYFGY •ASTGASNDNHYFGY
■ASTGASNDNHYFGY ■SQSGASNDNHYFGY ■SQSGASNDSHYFGY ■ ...
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G Gao, JM Wilson, L Vandenberghe… - EP Patent …, 2011 - freepatentsonline.com
1. An adeno-associated virus (AAV) comprising an AAV capsid of serotype hu.53 wherein the
AAVhu.53 capsid has at least 95% identity with the sequence of amino acids 204 to 734 of SEQ
ID NO: 186 and wherein the AAV further comprises a minigene having AAV inverted ...
Cached
NM Kotchey, K Adachi, M Zahid, K Inagaki… - Molecular …, 2011 - nature.com
Recombinant adeno-associated virus serotype 9 (rAAV9) vectors show robust in vivo transduction
by a systemic approach. It has been proposed that rAAV9 has enhanced ability to cross the vascular
endothelial barriers. However, the scientific basis of systemic administration of rAAV9 and ...
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CE Sanchez, TS Tierney, JT Gale… - Journal of …, 2011 - thejns.org
Abbreviations used in this paper: AAV2 = adeno-associated virus type 2; AAV2/2 = AAV2 serotype
2; CBA = CMV/chicken β-actin; CED = convection-enhanced delivery; CMV =
cytomegalovirus; EGFP = enhanced green fluorescent protein; GFAP = glial fibrillary ...
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