…, ML Drumm, PR Durie, MR Knowles, GR Cutting - Nature genetics, 2011 - nature.com A combined genome-wide association and linkage study was used to identify loci causing variation in cystic fibrosis lung disease severity. We identified a significant association (P = 3.34 × 10 −8 ) near EHF and APIP (chr11p13) in p.Phe508del homozygotes (n = 1,978). The ... Cited by 1 - Related articles - All 4 versions
…, J Cook, NF Fairweather, SM Cutting - Infection and …, 2011 - Am Soc Microbiol Clostridium difficile is a leading cause of nosocomial infection in the developed world. Two toxins, A and B, produced by most strains of C. difficile are implicated as virulence factors, yet only recently has the requirement of these for infection been investigated by genetic ... Related articles
JM Collaco, DM Green, GR Cutting… - American Journal of …, 2011 - Am Thoracic Soc From the Authors: The title of our article, although perhaps provocative, was intended to draw attention to and foster debate concerning optimal treat- ment for cystic fibrosis (CF) respiratory exacerbations to better serve patients with CF. Respiratory exacerbations are a major ...
DA Mancardi, F Jönsson, B Iannascoli… - The Journal of …, 2011 - Am Assoc Immnol K/BxN serum-induced passive arthritis was reported to depend on the activation of mast cells, triggered by the activating IgG receptor FcγRIIIA, when engaged by IgG1 autoantibodies present in K/BxN serum. This view is challenged by the fact that FcγRIIIA-deficient mice ... Cited by 2 - Related articles - All 4 versions
D Baumjohann, T Okada… - The Journal of Immunology, 2011 - Am Assoc Immnol T follicular helper (T FH ) cells are central to the development and regulation of T cell-dependent humoral immune responses. The transcriptional repressor BCL6 is required for T FH responses, but the kinetics of BCL6 protein expression in activated CD4 + T cells have ...
沪公网安备号：31010402006960 （网站）31010405000484 （蝌蝌APP）
安全保密
