W Löscher - Seizure, 2011 - Elsevier ... Since epilepsy is characterized by spontaneous recurrent seizures (SRS), a test such as the MEStest, in which an acute seizure is electrically induced in a normal non-epileptic animal, cannot represent a model of epilepsy. ... Cited by 2 - Related articles - All 4 versions
[PDF] from krakow.plM Czuczwar, K Czuczwar, J Cięszczyk… - Pharmacological …, 2011 - if-pan.krakow.pl ... Total brain VPA concentration Pharmacokinetic evaluation of total brain AED con- centration was only performed in mice treated with the combination of NEF and VPA at the dose corre- sponding to the ED# value of VPA calculated from the MES-test. ... View as HTML
S Shehab, A Al-Nahdi, F Al-Zaabi… - Neurobiology of …, 2011 - Elsevier ... Subsequently, we investigated whether the acute stimulation with the most powerful SNr inhibition producing frequency could suppress tonic seizures using the MEStest. Part of this study had appeared as an abstract (Shehab et al., 2010). ... All 2 versions
[HTML] from nih.govS Eskandari, J Varshosaz, M Minaiyan… - International Journal …, 2011 - ncbi.nlm.nih.gov ... kindling. The MES and PTZ tests are models of acute (reactive or provoked) seizures.12 The MEStest, which is a widely used animal model, identifies the drug activity against generalized tonic–clonic and partial seizures.13,14. ... Related articles - All 5 versions
S Pandey, S Shukla, D Pandey… - Russian Chemical …, 2011 - turpion.org ... Compound ED50 /mg kg71 PI 17a 42.2 1.9 17b 110.0 >4.5 20 173.45 0.80 7-Chloroxanthone derivatives with 2-amino or 2-N-me- thylaminobutan-1-ol fragments have shown noticeable anti- convulsant activity in the MEStest in mice (ip). ... Related articles - All 4 versions
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