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[HTML] from nih.govRYUE GAO, P MUKHOPADHYAY… - Molecular medicine …, 2011 - ncbi.nlm.nih.gov
Nucleotide reverse transcriptase inhibitors, such as zidovudine (azidothymidine, AZT) and
stavudine, represent a class of approved antiretroviral agents for highly active antiretroviral
therapy, which prolongs the life expectancy of patients infected with human- ...
Related articles - All 2 versions
[PDF] from mdpi.comHY Ji, KH Liu, H Lee, SR Im, HJ Shim, M Son… - Molecules, 2011 - mdpi.com
... UGT1A4-mediated trifluoperazine N-glucuronidation and UGT2B7-mediated azidothymidine
glucuronidation were not inhibited by treatment with corydaline (Table 2). Corydaline inhibited
UGT1A1-catalyzed 17β-estradiol ... UGT2B7 Azidothymidine glucuronidation ...
[PDF] from mdpi.comB Macchi, E Balestrieri, A Ascolani, S Hilburn… - Viruses, 2011 - mdpi.com
... from patients with HTLV-1-associated myelopathy. Sensitivity to azidothymidine (AZT), lamivudine
(3TC), tenofovir (TDF) and three phosphonated carbocyclic 2‟-oxa-3‟aza nucleosides (PCOANs)
was assessed in a RT inhibitor assay. With the exception of 3TC, ...
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J Liu, D Obando, V Liao, T Lifa… - European journal of medicinal …, 2011 - Elsevier
... This concept is well illustrated in the case in which adamantyl-1-acetic acid was
appended via an ester bond to the AIDS drug azidothymidine to produce a prodrug
with improved carriage across the blood brain barrier. Intravenous ...
All 3 versions
MM Makatini, K Petzold, SN Sriharsha… - Bioorganic & medicinal …, 2011 - Elsevier
... Abbreviations: PIs, Protease inhibitors; HIV-PR, HIV protease; AZT, azidothymidine;
CNS, Central Nervous System; PCU, Pentacycloundecane. ... 8, 16, 17 Adamantane was
previously coupled to azidothymidine (AZT). 8, 18 Brookes et al. ...
All 3 versions

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