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C Prasse, M Wagner, R Schulz… - Environmental science & …, 2011 - ACS Publications
The biotransformation of the two antiviral drugs, acyclovir (ACV) and penciclovir (PCV), was investigated
in contact with activated sludge. Biodegradation kinetics were determined, and transformation
products (TPs) were identified using Hybrid Linear Ion Trap- FT Mass Spectrometry (LTQ ...
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MA McMahon, TL Parsons, L Shen… - Journal of …, 2011 - Am Soc Microbiol
Acyclovir, a nucleoside analog, is thought to be specific for the human herpesviruses because
it requires a virally encoded enzyme to phosphorylate it to acyclovir monophosphate.
Recently, acyclovir triphosphate was shown to be a direct inhibitor of human ...
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JM Baeten, J Lingappa, I Beck… - Journal of Infectious …, 2011 - jid.oxfordjournals.org
Recent in vitro studies suggest that acyclovir may directly inhibit HIV-1 replication and can select
for a specific HIV-1 reverse transcriptase mutation (V75I) with concomitant loss of an
anti-HIV-1 effect. We tested for HIV-1 genotypic resistance at reverse transcriptase codon ...
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C Tanton, HA Weiss, J LeGoff… - Sexually Transmitted …, 2011 - sti.bmj.com
Contributors CT, HAW, DWJ, JC, RJH and DAR designed the study. CT, DWJ and JC contributed
to the data collection. JLG and LB advised on and oversaw the laboratory analyses. Statistical
analyses were performed by CT with guidance from HAW, TCC and RJH. CT, HAW and ...
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MA McMahon, TL Parsons, L Shen… - Journal of …, 2011 - Am Soc Microbiol
Consistent Inhibition of HIV-1 Replication by Acyclovir in CD4+ T Cells Without Detection of 1
2 Human Herpes Viruses 3 4 5 Moira A. McMahon1, Teresa L. Parsons2, Lin Shen1, Janet
D. Siliciano3, Robert F. Siliciano3,4 6 7 8 From the 1Department of Pharmacology and ...
All 2 versions

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