J Bartek… - Nature, 2011 - nature.com Cyclin D1 has a crucial role in the cell cycle and is often overexpressed in cancer. Piotr Sicinski and colleagues report an unexpected function for cyclin D1 in DNA repair that is independent of its known CDK-dependent role. Cyclin D1 is recruited to sites of DNA damage and ... All 3 versions
S Jirawatnotai, Y Hu, W Michowski, JE Elias… - Nature, 2011 - nature.com Cyclin D1 is a component of the core cell cycle machinery 1 . Abnormally high levels of cyclin D1 are detected in many human cancer types 2 . To elucidate the molecular functions of cyclin D1 in human cancers, we performed a proteomic screen for cyclin D1 protein partners in ... All 3 versions
A Kumagai, A Shevchenko… - The Journal of Cell …, 2011 - jcb.rupress.org Treslin, a TopBP1-interacting protein, is necessary for deoxyribonucleic acid (DNA) replication in vertebrates. Association between Treslin and TopBP1 requires cyclin-dependent kinase (Cdk) activity in Xenopus laevis egg extracts. We investigated the mechanism and ... Related articles - All 5 versions
M Alvarez-Fernandez, VA Halim, M Aprelia… - Journal of Biological …, 2011 - ASBMB The forkhead transcription factor FoxM1 controls expression of a large number of genes that are specifically expressed during the G2 phase of the cell cycle. Throughout most of the cell cycle, FoxM1 activity is restrained by an auto-inhibitory mechanism, involving a repressor ...
V Liberal, HS Martinsson-Ahlzén… - Proceedings of the …, 2011 - ncbi.nlm.nih.gov Cyclin-dependent kinase subunit (Cks) proteins are small cyclin-dependent kinase-interacting proteins that are frequently overexpressed in breast cancer, as well as in a broad spectrum of other human malignancies. However, the mechanistic link between Cks protein ... All 2 versions
沪公网安备号：31010402006960 （网站）31010405000484 （蝌蝌APP）
安全保密
