推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-33361733,021-34243363

chinasupport@letpub.com

登录 注册 新注册优惠

B Rooney, H O'Donovan, A Gaffney, M Browne… - FEBS letters, 2011 - Elsevier
We describe the activation of Wnt signalling in mesangial cells by CCN2. CCN2 stimulates phosphorylation
of LRP6 and GSK-3β resulting in accumulation and nuclear localisation of β-catenin, TCF/LEF
activity and expression of Wnt targets. This is coincident with decreased phosphorylation ...
Cited by 3 - Related articles - All 3 versions
S Khan, S Lakhe-Reddy, JH McCarty… - The American Journal of …, 2011 - Elsevier
Integrins are heterodimeric receptors that regulate cell adhesion, migration, and apoptosis. Integrin
αvβ8 is most abundantly expressed in kidney and brain, and its major ligand is latent transforming
growth factor-β (TGF-β). Kidney αvβ8 localizes to mesangial cells, which appose ...
Cited by 1 - Related articles - All 4 versions
F Krötz - American Journal of Physiology-Renal Physiology, 2011 - Am Physiological Soc
Toll-like receptor subtype 3 (TLR3) is a unique member of the TLR family of innate immune
receptors. In contrast to most TLRs, which are can be activated by either bacterial, fungal, or
unknown stimuli, TLR3 is the only TLR subtype that can be activated by double-stranded ...
Related articles - All 3 versions
MS Simonson… - Journal of Biological Chemistry, 2011 - ASBMB
Endothelin-1 (ET-1), a potent vasoconstrictor, has been implicated in the pathogenesis of collagen
accumulation, extracellular matrix remodeling, and renal and cardiac fibrosis in diabetes.
However, the mechanism by which ET-1 promotes collagen accumulation remains ...
Related articles - All 3 versions
I Loeffler, U Hopfer, D Koczan… - Journal of the American …, 2011 - Am Soc Nephrol
Mesangial cells in diabetic mice and human kidneys with diabetic nephropathy exhibit increased
type VIII collagen, a nonfibrillar protein that exists as a heterodimer composed of α1(VIII) and
α2(VIII), encoded by Col8a1 and Col8a2, respectively. Because TGF-β1 promotes the ...
All 4 versions

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海    网站备案号:沪ICP备10217908号-1    沪公网安备号:31010402006960 (网站)31010405000484 (蝌蝌APP)

增值电信业务经营许可证:沪B2-20211595    网络文化经营许可证:沪网文[2023]2004-152号

礼翰商务信息咨询(上海)有限公司      办公地址:上海市徐汇区漕溪北路88号圣爱大厦1803室