[HTML] from plos.orgAL Price, A Helgason, G Thorleifsson, SA McCarroll… - PLoS genetics, 2011 - dx.plos.org An important goal in biology is to understand how genotype affects gene expression. Because gene expression varies across tissues, the relationship between genotype and gene expression may be tissue-specific. In this study, we used heritability approaches to study the ... Related articles - Cached - All 3 versions
BL Browning… - The American Journal of Human Genetics, 2011 - Elsevier We present a method, fastIBD, for finding tracts of identity by descent (IBD) between pairs of individuals. FastIBD can be applied to thousands of samples across genome-wide SNP data and is significantly more powerful for finding short tracts of IBD than existing methods for ... Cited by 5 - Related articles - All 2 versions
[HTML] from nih.govC Rödelsperger, P Krawitz, S Bauer, J Hecht… - …, 2011 - Oxford Univ Press Motivation: Next-generation sequencing and exome-capture technologies are currently revolutionizing the way geneticists screen for disease-causing mutations in rare Mendelian disorders. However, the identification of causal mutations is challenging due to the sheer number of ... Cited by 1 - Related articles - All 8 versions
[PDF] from psu.eduB Kirkpatrick, S Li, R Karp… - Research in Computational …, 2011 - Springer Abstract. Can we find the family trees, or pedigrees, that relate the haplotypes of a group of individuals? Collecting the genealogical infor- mation for how individuals are related is a very time-consuming and expensive process. Methods for automating the construction of pedi- ... Cited by 1 - Related articles - All 10 versions
R Bell, SM Herring, N Gokul, M Monita… - Circulation: …, 2011 - Am Heart Assoc Methods and Results—We compared genotypes at nearly 10 000 SNPs obtained for the hypertension end-organ injury-susceptible spontaneously hypertensive rat (SHR)-A3 (SHRSP, SHR-stroke prone) line and the injury-resistant SHR-B2 line. This revealed that that the 2 lines were ... Related articles - All 3 versions
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