NM Laird… - The Fundamentals of Modern Statistical Genetics, 2011 - Springer In the absence of genetic data at the molecular level, the results of heritability, aggregation and/or segregation analysis provided the first hints about the presence of genetic effects and, consequently, the existence of a disease gene. Without infor- mation on the etiology ...
L Salmaso, R Arboretti, L Corain… - Permutation Testing for …, 2011 - Springer ... 2 1 Introduction Page 3. is the frequency of the ''1'' allele at locus 1 in the general population and q1 is the population frequency of the ''1'' allele at locus 2. The coefficient D ranges from –0.25 (linkageequilibrium) to 0.25 (linkagedisequilibrium). ... Cited by 40 - Related articles
[HTML] from nih.govMD Robbins, SC Sim, W Yang… - Journal of …, 2011 - Soc Experiment Biol The history of tomato (Solanum lycopersicum L.) improvement includes genetic bottlenecks, wild species introgressions, and divergence into distinct market classes. This history makes tomato an excellent model to investigate the effects of selection on genome variation. A ... Related articles - All 6 versions
D Van Inghelandt, JC Reif, BS Dhillon… - TAG Theoretical and …, 2011 - Springer Abstract Association mapping is based on linkage dis- equilibrium (LD) resulting from historical recombinations and helps understanding the genetic basis of complex traits. Many factors affect LD and, therefore, it must be determined empirically in the germplasm under investigation ... Cited by 2 - Related articles - All 3 versions
F Úbeda, D Haig, MM Patten - … of the Royal …, 2011 - rspb.royalsocietypublishing.org Linkage disequilibrium (LD) is an association between genetic loci that is typically transient. Here, we identify a previously overlooked cause of stable LD that may be pervasive: sexual antagonism. This form of selection produces unequal allele frequencies in males and ... Cited by 3 - Related articles - All 4 versions