Z Jin… - Journal of Biological Chemistry, 2011 - ASBMB ... For the past 2 decades, there has been considerable controversy regarding the role of induced fit in enzymespecificity (6, 7). In the DNA polymerase field, the debate has focused mainly on whether the substrate-induced conformational change is rate-limiting and whether it can ... Cited by 2 - Related articles - All 4 versions
O Schilling, PF Huesgen, O Barré… - Nature Protocols, 2011 - nature.com ... PICS is a unique approach that uses proteome-derived peptide libraries and harnesses natural sequence diversity to probe for cleavage sequence and enzymespecificity. When derived from a fully sequenced organism, peptide ... All 3 versions
K Althaus, U Strobel, TE Warkentin… - Thrombosis …, 2011 - ncbi.nlm.nih.gov BACKGROUND: IgG-specific anti-PF4/heparin enzyme-immunoassays (EIAs) are sensitive but not specific for platelet-activating antibodies, the cause of heparin-induced thrombocytopenia (HIT). Two features of EIA reactivity predict for presence of HIT antibodies - the magnitude ... Cited by 1
A Dhayalan, S Kudithipudi, P Rathert… - Chemistry & Biology, 2011 - Elsevier ... 9. Since methylation of several substrates is performed in competition on the SPOT membranes, the methylation levels of different peptide spots correspond to k cat /K D values, which is a well-established measure of enzymespecificity (see Supplemental Information S1 in ... Cited by 1 - Related articles - All 2 versions
J Hall - 2011 - dspace.ndlr.ie ... Title: Introduction to enzymes : final assessment level 8. Description: Interactive material created as part of the CeLLS project (www.cellsproject.org) covering the topic of enzymes, in particular the nomenclature, what they do, how they work and enzymespecificity. ... Cached - All 2 versions
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