A Hoelz… - Annual Review of Biochemistry, 2011 - annualreviews.org In eukaryotic cells, the spatial segregation of replication and transcription in the nucleus and translation in the cytoplasm imposes the requirement of transporting thousands of macromolecules between these two compartments. Nuclear pore complexes (NPCs) are the sole ... Related articles
KN Noble, EJ Tran, AR Alcázar-Román… - Genes & …, 2011 - genesdev.cshlp.org Essential messenger RNA (mRNA) export factors execute critical steps to mediate directional transport through nuclear pore complexes (NPCs). At cytoplasmic NPC filaments, the ATPase activity of DEAD-box protein Dbp5 is activated by inositol hexakisphosphate (IP 6 )-bound ... Cited by 4 - Related articles - All 2 versions
S Ledoux… - Genes & Development, 2011 - genesdev.cshlp.org Dbp5 is one of 25 DEAD-box RNA-dependent ATPases in budding yeast. One or more DEAD-box proteins are associated with every major step of RNA processing (for recent reviews, see Cordin et al. 2006; Jarmoskaite and Russell 2010). This family of proteins is ... Related articles - All 2 versions
[HTML] from plos.orgKE Ocwieja, TL Brady, K Ronen, A Huegel… - PLoS pathogens, 2011 - dx.plos.org HIV continues to be responsible for approximately two million deaths worldwide each year. As part of the viral replication cycle, the viral cDNA is transported through the nuclear pore into the nucleus where it integrates into the host cell genome. HIV integrates non-randomly, likely ... Cited by 2 - Related articles - Cached - All 6 versions
DL Updike, SJ Hachey, J Kreher… - The Journal of Cell …, 2011 - jcb.rupress.org The immortal and totipotent properties of the germ line depend on determinants within the germ plasm. A common characteristic of germ plasm across phyla is the presence of germ granules, including P granules in Caenorhabditis elegans, which are typically associated ... Cited by 2 - Related articles - All 3 versions
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