G Kozlov, AY Denisov, M Girard, MJ Dicaire… - Journal of Biological …, 2011 - ASBMB ... The C terminus of the protein contains an HEPN (higher eukaryotes and prokaryotes nucleotide-binding) domain of unknown function. Here, we determined the high-resolution 1.9-Å crystal structure of the HEPN domain from human sacsin. ... Related articles
E Guth, M Thommen… - Journal of Biological Chemistry, 2011 - ASBMB ... oxygen and nitrogen species deployed by macrophages (6). The M. tuberculosis proteasomal system plays a critical role in bacterial resistance to reactive nitrogen species both in vitro and in vivo (7) and makes use of a ubiquitin-like molecule, termed Pup (prokaryotic ubiquitin ... Related articles - All 3 versions
MP Cohen - Configurations, 2011 - muse.jhu.edu ... Barnes and Dupré argue that "[p]rokaryotes are overwhelmingly the most common organisms, and for 80% of the history of life on the planet were the only organisms, so it would be entirely appropriate for a discussion of genomes to take prokaryotic genomes as paradigms." 20 ...
[HTML] from nih.govY Shao, EM Harrison, D Bi, C Tai, X He… - Nucleic Acids …, 2011 - Oxford Univ Press ... Gura_2470 (Figure 1D). The putative toxin protein (yet to be experimentally characterized), Gura_2470, contains a MNT (minimal nucleotidyltransferase) domain, while its cognate putative antitoxin, Gura_2469, harbors a HEPN (higher eukaryotes and prokaryotes nucleotide ... Cited by 3 - Related articles - All 6 versions
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