C Prasse, M Wagner, R Schulz… - Environmental science & …, 2011 - ACS Publications The biotransformation of the two antiviral drugs, acyclovir (ACV) and penciclovir (PCV), was investigated in contact with activated sludge. Biodegradation kinetics were determined, and transformation products (TPs) were identified using Hybrid Linear Ion Trap- FT Mass Spectrometry (LTQ ... Related articles - All 3 versions
MA McMahon, TL Parsons, L Shen… - Journal of …, 2011 - Am Soc Microbiol Acyclovir, a nucleoside analog, is thought to be specific for the human herpesviruses because it requires a virally encoded enzyme to phosphorylate it to acyclovir monophosphate. Recently, acyclovir triphosphate was shown to be a direct inhibitor of human ... Related articles - All 2 versions
JM Baeten, J Lingappa, I Beck… - Journal of Infectious …, 2011 - jid.oxfordjournals.org Recent in vitro studies suggest that acyclovir may directly inhibit HIV-1 replication and can select for a specific HIV-1 reverse transcriptase mutation (V75I) with concomitant loss of an anti-HIV-1 effect. We tested for HIV-1 genotypic resistance at reverse transcriptase codon ... Related articles - All 5 versions
C Tanton, HA Weiss, J LeGoff… - Sexually Transmitted …, 2011 - sti.bmj.com Contributors CT, HAW, DWJ, JC, RJH and DAR designed the study. CT, DWJ and JC contributed to the data collection. JLG and LB advised on and oversaw the laboratory analyses. Statistical analyses were performed by CT with guidance from HAW, TCC and RJH. CT, HAW and ... Related articles - All 3 versions
MA McMahon, TL Parsons, L Shen… - Journal of …, 2011 - Am Soc Microbiol Consistent Inhibition of HIV-1 Replication by Acyclovir in CD4+ T Cells Without Detection of 1 2 Human Herpes Viruses 3 4 5 Moira A. McMahon1, Teresa L. Parsons2, Lin Shen1, Janet D. Siliciano3, Robert F. Siliciano3,4 6 7 8 From the 1Department of Pharmacology and ... All 2 versions
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