MRP Coombs, ME Belderbos… - Expert Review of …, 2011 - expert-reviews.com Figure 2. Mechanisms of adenosine-mediated modulation of endotoxin-induced cytokine production: inhibition of TNF and enhancement of IL-6 and IL-10. Endotoxin-induced activation of the TLR-4 receptor complex results in activation of MyD88 and TRIF signaling ...
CMR Power, ME Belderbos… - Expert review of anti- …, 2011 - ncbi.nlm.nih.gov Adenosine is an endogenous purine metabolite whose concentration in human blood plasma rises from nanomolar to micromolar concentrations during the inflammatory process. Leukocytes express seven-transmembrane adenosine receptors whose engagement modulates Toll- ...
…, KL Shultz, HF Coombs III… - Journal of Bone and …, 2011 - Wiley Online Library The distal end of mouse chromosome 1 (Chr 1) harbors quantitative trait loci (QTLs) that regulate bone mineral density (BMD) and share conserved synteny with human chromosome 1q. The objective of this article was to map this mouse distal Chr 1 region and identify gene(s) ... Cited by 1 - Related articles - All 4 versions
PY Sato, W Coombs, X Lin, O Nekrasova… - Circulation …, 2011 - Am Heart Assoc Rationale: The early description of the intercalated disc defined 3 structures, all of them involved in cell-cell communication: desmosomes, gap junctions, and adherens junctions. Current evidence demonstrates that molecules not involved in providing a physical continuum between ... Related articles - All 3 versions
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