TL Willliams, BR Johnson, B Urbanc… - The Biochemical …, 2011 - ncbi.nlm.nih.gov Amyloid-Beta peptide (Ab) assembles to form amyloid fibres that accumulate in senile plaques associated with Alzheimer's disease (AD). The major constituent, a 42-residue Ab peptide, has the propensity to assemble and form soluble and potentially cytotoxic oligomers as well ... All 2 versions
[PDF] from omicsonline.orgT Valdes-Gonzalez, N Goto-Inoue… - J Glycom …, 2011 - omicsonline.org ... Combination of TLC-Blot and MALDI- TOF –Special Reference to Human Brain Ganglioside Molecular Species ... Then we analyzed ganglioside molecular species obtained from different brain regions by using MS imaging technology. ... View as HTML
[HTML] from plos.orgI Popa, N Therville, S Carpentier, T Levade… - PloS one, 2011 - dx.plos.org Activation of an acid sphingomyelinase (aSMase) leading to a biosynthesis of GD3 disialoganglioside has been associated with Fas-induced apoptosis of lymphoid cells. The present study was undertaken to clarify the role of this enzyme in the generation of gangliosides during apoptosis ... Related articles - Cached - All 3 versions
[PDF] from biochemj.orgTL Williams, BRG Johnson, B Urbanc, ATA Jenkins… - 2011 - biochemj.org 1 Alzheimer's Aβ42 oligomers but not fibrils simultaneously bind to and cause damage to ganglioside containing lipid membranes ... Binding of the oligomers may be in part mediated by the GM1 ganglioside receptors showing a 1.8-fold increase in oligomeric Aβ binding and a 2- ... Related articles - View as HTML
F Kreutz, RL Frozza, AC Breier… - Neurochemistry …, 2011 - Elsevier The effect of Aβ25–35 peptide, in its fibrillar and non-fibrillar forms, on ganglioside expression in organotypic hippocampal slice cultures was investigated. Gangliosides were endogenously labeled with d-[1-C 14 ] galactose and results showed that Aβ25–35 affected ganglioside ... All 2 versions