[PDF] from harvard.eduS Paust… - Nature immunology, 2011 - nature.com Natural killer (NK) cells are bone marrow–derived granular lymphocytes that have a key role in immune defense against viral and bacterial infections and malignancies. NK cells are traditionally defined as cells of the innate immune response because they lack RAG recombinase– ... Cited by 2 - Related articles - All 5 versions
[HTML] from asm.orgEA Mack, LE Kallal, DA Demers… - mBio, 2011 - Am Soc Microbiol Natural killer (NK) cells are equipped to innately produce the cytokine gamma interferon (IFN-γ) in part because they basally express high levels of the signal transducer and activator of transcription 4 (STAT4). Type 1 interferons (IFNs) have the potential to activate STAT4 ...
S Lopez-Vergès, JM Milush… - Proceedings of the …, 2011 - National Acad Sciences Natural killer (NK) cells are a subset of lymphocytes com- prising 5% to 20% of peripheral blood mononuclear cells (PBMCs) in humans (1). NK cells participate in the innate im- mune response and play an important role in the defense against viral infections and tumor surveillance, ...
SJ Coles, ECY Wang, S Man, RK Hills, AK Burnett… - Leukemia, 2011 - nature.com Upregulation of the immunosuppressive cell surface glycoprotein, CD200, is a common feature of acute myeloid leukemia (AML) and is associated with poor patient outcome. We investigated whether CD200 overexpression on AML cells could specifically compromise patient ... Related articles - All 4 versions
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