JL Herzog, JA Solomon, Z Draelos… - Journal of drugs in …, 2011 - ncbi.nlm.nih.gov Objective: To investigate the efficacy, safety and tolerability of topical nalmefene (SRD174), a long acting opioid antagonist for the management of pruritus associated with atopic dermatitis (AD). Design: Double-blind, vehicle-controlled, randomized, cross-over trial. Setting: ...
IV Ukrainets, LV Sidorenko, AA Davidenko… - …, 2011 - Wiley Online Library ChemInform Abstract: 4-Hydroxy-2-quinolones. Part 174. Hydrochlorides of [(Alkylamino)alkyl]amides of 1-Allyl-4-hydroxy-6,7-dimethoxy-2-oxo-1,2-dihydroquinoline-3-carboxylic Acid — A New Class of Opiod Receptor Antagonists. ... In pharmacological tests, ...
E Dudley, F Haasharpsharpler… - Expert Review of …, 2011 - ingentaconnect.com ... In addition to this specific ana lysis of target proteins/peptides, studies were also undertaken that focused on the 'opiod peptide excess' theory. This hypothesis represents the view that an accu- mulation of exogenously generated ... Related articles - All 3 versions
S Willms, C Ilies, B Bein… - European Journal of …, 2011 - journals.lww.com ... Study: Surgical Pleth Index (SPI), derived by finger plethysmography, was introduced to detect nociceptive stimulation and is dependent on analgesic drug concentration [1, 2]. The use of SPI reduced the number of unwanted intraoperative events and opiod consumption during ... Related articles
H Svenningsen… - Nursing in Critical Care, 2011 - Wiley Online Library ... elderly patients. Aims: The purpose of this study was to evaluate the incidence of delirium in adult intensive care patients in Denmark and to identify correlations between delirium, sedatives, opiod analgesics and age. Methods ... Related articles - All 2 versions