[PDF] from harvard.eduW Truccolo, JA Donoghue, LR Hochberg… - Nature …, 2011 - nature.com Epileptic seizures are traditionally characterized as the ultimate expression of monolithic, hypersynchronous neuronal activity arising from unbalanced runaway excitation. Here we report the first examination of spike train patterns in large ensembles of single neurons during seizures in persons ... Cited by 3 - All 4 versions
[HTML] from plos.orgEH Seppälä, TS Jokinen, M Fukata, Y Fukata… - PLoS Genet, 2011 - dx.plos.org Major remodeling of the neuronal synaptic network occurs during childhood. The quadrillion synapses formed till the end of age two are trimmed to 500 trillion by age 10 through a selective process of strengthening of ideal connections, removal of redundant ones, and formation ... Cited by 1 - Cached
I Manna, A Gambardella, A Bianchi, P Striano… - Epilepsia, 2011 - Wiley Online Library A splice site variation (c.603-91G>A or rs3812718) in the SCN1A gene has been claimed to influence efficacy and dose requirements of carbamazepine and phenytoin. We investigated the relationship between c.603-91G>A polymorphism and response to antiepileptic drugs ... Related articles - All 3 versions
EC Wirrell, BR Grossardt, EL So… - Epilepsia, 2011 - Wiley Online Library Purpose: To compare long-term outcome in a popula- tion-based group of children with cryptogenic versus symp- tomatic focal epilepsy diagnosed from 1980 to 2004 and to define the course of epilepsy in the cryptogenic group. Methods: We identified all children residing in Olmsted ... Related articles - All 4 versions
J Anderson, P Harder… - Journal of Neurology, …, 2011 - jnnp.bmj.com Throughout most of his adult life, he received high doses of phenytoin (PHT 600 mg/day) and carbamazepine (CBZ 1400–1600 mg/day) without seizure control from the sequential addition of valproate, primidone, clonazepam, topiramate and lamotrigine at maximum tolerated ... Cited by 1 - Related articles - All 5 versions
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