AJ Hickey… - Pharmaco-Complexity, 2011 - Springer The preformulation and formulation of new chemical entities (NCEs) have evolved considerably in the past 50 years, being driven largely by dramatic changes in the regulation of drug prod- ucts. The objective of this chapter is to discuss examples of several well-known and ... Related articles
[HTML] from aidsrestherapy.comAB Sassi, KE Bunge, BL Hood… - AIDS Research and …, 2011 - aidsrestherapy.com RC-101, a cationic peptide retrocyclin analog, has in vitro activity against HIV-1. Peptide drugs are commonly prone to conformational changes, oxidation and hydrolysis when exposed to excipients in a formulation or biological fluids in the body, this can affect product efficacy. We aimed ... Cached
H Agashe, P Lagisetty, K Sahoo, D Bourne… - Journal of Nanoparticle …, 2011 - Springer Abstract 3,5-Bis(2-fluorobenzylidene)-4-piperidone (EF24) is an anti-proliferative diphenyldifluoroketone analog of curcumin with more potent activity. The authors describe a liposome preparation of EF24 using a ''drug-in-CD-in liposome'' approach. An aqueous solution of EF24 and ... Related articles - All 3 versions
L Perioli, V Ambrogi, M Nocchetti, M Sisani… - Applied Clay …, 2011 - Elsevier Oral administration of poorly soluble drugs represents a challenge for the pharmaceutical industries. This research proposes the realization of host–guests composites in which the model drug furosemide (FURO), labeled in class IV of BCS, was chosen as guest whereas ...