KR Tan, U Rudolph… - Trends in neurosciences, 2011 - Elsevier Benzodiazepines are widely used clinically to treat anxiety and insomnia. They also induce muscle relaxation, control epileptic seizures, and can produce amnesia. Moreover, benzodiazepines are often abused after chronic clinical treatment and also for recreational purposes. ... Cited by 1 - Related articles - All 3 versions
TI Saari, M Uusi-Oukari, J Ahonen… - Pharmacological Reviews, 2011 - ASPET GABA is the major inhibitory neurotransmitter in the central nervous system (CNS). The type A GABA receptor (GABA A R) system is the primary pharmacological target for many drugs used in clinical anesthesia. The α1, β2, and γ2 subunit-containing GABA A Rs located in the ... Cited by 1 - Related articles - All 3 versions
U Rudolph… - Nature Reviews Drug Discovery, 2011 - nature.com GABA A (γ-aminobutyric acid, type A) receptors are a family of ligand-gated ion channels that are essential for the regulation of central nervous system function. Benzodiazepines — which non-selectively target GABA A receptors containing the α1, α2, α3 or α5 subunits — have ...
MP Wilson, K MacDonald, GM Vilke… - The Journal of …, 2011 - ncbi.nlm.nih.gov BACKGROUND: Pharmacologic management of the agitated emergency department patient is controversial. The combination of olanzapine + benzodiazepines is not recommended by the manufacturer, but a recent report suggested harm only if the patient was intoxicated. ... All 2 versions
S Kisely, A Smith, I Sketris… - … Meeting of the …, 2011 - espace.library.uq.edu.au Kisely, Steve, Smith, Alesha, Sketris, Ingrid, Cooke, Charmaine, Gardner, David and Tett, Sue (2008). Is there an association between the range of benzodiazepines available and the quality of prescribing?: An international comparison of Canada and Australia using ... Cached - All 2 versions