CC Morales-Manrique, A Palepu… - Substance Use & …, 2011 - informahealthcare.com We examined the quality of life (QoL) of 149 patients who were recruited in 2005 at outpatient treatment centers for cocaine dependence in Spain. Important life areas and life areas with potential need and interest to change in order to improve the QoL were analyzed in terms of ... Related articles - All 3 versions
RP Waters… - Pharmacology, biochemistry, and behavior, 2011 - ncbi.nlm.nih.gov Stress is a well-known risk factor in relapse to drug abuse. Several forms of stress in animals have been used with varied degrees of success to elicit reinstatement of drug-seeking after chronic drug self-administration. Here, we tested the ability of the benzodiazepine (BZ) inverse ...
EP Bello, Y Mateo, DM Gelman, D Noaín… - Nature …, 2011 - nature.com Dopamine (DA) D 2 receptors expressed in DA neurons (D 2 autoreceptors) exert a negative feedback regulation that reduces DA neuron firing, DA synthesis and DA release. As D 2 receptors are mostly expressed in postsynaptic neurons, pharmacological and genetic approaches ... Cited by 1 - All 3 versions
MH James, JL Charnley, EM Levi… - … scientific journal of …, 2011 - Cambridge Univ Press Abstract Orexinergic signalling is critical to drug relapse-like behaviour ; however, the CNS sites(s) of action remain unknown. Two candidate brain regions are the paraventricular thalamus (PVT) and ventral tegmental area (VTA). We assessed the effect of intra-PVT or -VTA ... Related articles - All 3 versions
RA Wise… - Nature Reviews Neuroscience, 2011 - nature.com The subjective effects of intravenous cocaine are felt almost immediately, and this immediacy plays an important part in the drug's rewarding impact. The primary rewarding effect of cocaine involves blockade of dopamine reuptake; however, the onset of this action is too late to ... All 3 versions