D Morrone, ML Hillwig, MM Mead… - The Biochemical …, 2011 - ncbi.nlm.nih.gov The evolution of natural products biosynthetic pathways can be envisioned to occur via a number of mechanisms. Here we provide evidence that latent plasticity plays a role in such metabolic evolution. In particular, rice (Oryza sativa) produces both ent- and syn- copalyl ... Cited by 1 - Related articles - All 3 versions
CI Keeling, LL Madilao, P Zerbe, HK Dullat… - Journal of Biological …, 2011 - ASBMB Diterpene resins acids play an important role in conifer defence against herbivores and pathogens (1,2). They are biosynthesized by the cyclization of geranylgeranyl diphosphate by single- or multi-product diterpene synthases (Fig. 1) and the subsequent oxidation by cytochromes ... Related articles - All 2 versions
M Köksal, H Hu, RM Coates, RJ Peters… - Nature Chemical …, 2011 - nature.com (a) The cyclization reaction catalyzed by CPS is the first committed step of gibberellin biosynthesis in Arabidopsis thaliana. Diterpene analogs (S)-15-aza-14,15-dihydrogeranylgeranyl thiolodiphosphate (1) and 13-aza-13,14-dihydrocopalyl diphosphate (2) partially mimic the substrate and ... All 3 versions
CI Keeling, LL Madilao, P Zerbe, HK Dullat… - Journal of Biological …, 2011 - ASBMB The levopimaradiene/abietadiene synthase from Norway spruce (Picea abies; PaLAS) has previously been reported to produce a mixture of four diterpene hydrocarbons when incubated with geranylgeranyl diphosphate as the substrate: levopimaradiene, abietadiene, neoabietadiene, and ... Related articles
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