[PDF] from goodsamhosp.orgJ Hsia, JG MacFadyen, J Monyak… - Journal of the American …, 2011 - Elsevier During a median follow-up of 2 years (range up to 5 years), rates of the primary trial endpoint were 1.18, 0.86, and 0.44 per 100 person-years in the placebo group (n = 8,150) and rosuvastatin groups without LDL-C <50 mg/dl (n = 4,000) or with LDL-C <50 mg/dl (n = 4,154), ... Cited by 2 - Related articles - All 6 versions
SR Meisel, XP Xu, TS Edgington… - … of atherosclerosis and …, 2011 - ncbi.nlm.nih.gov Aim: Oxidized low-density lipoprotein (oxLDL) interacts with macrophages and is implicated in atherogenesis. Macrophages are also the major source within the atherosclerotic plaque of tissue factor (TF), the membrane-bound glycoprotein receptor that triggers the ...
T Karasawa, A Takahashi, R Saito… - … and Vascular Biology, 2011 - Am Heart Assoc Methods and Results— Transgenic mice that overexpress SREBP-1c in the liver and SREBP-1-deficient mice were crossed with low-density lipoprotein receptor (LDLR)–deficient mice, and the plasma lipids and atherosclerosis were analyzed. Hepatic SREBP-1c ... All 3 versions
Y Shi, F Cosentino, GG Camici… - … and Vascular Biology, 2011 - Am Heart Assoc Methods and Results—Incubation of human aortic endothelial cells with oxLDL led to phosphorylation of p66 Shc at Ser36. Inhibition of lectin-like oxLDL receptor-1 prevented p66 Shc phosphorylation, confirming that this effect is mediated by lectin-like oxLDL receptor-1. ...
VR Babaev, RP Runner, D Fan… - … and Vascular Biology, 2011 - Am Heart Assoc Methods and Results— We transplanted wild-type (WT), Mal1 –/– , or aP2 –/– bone marrow into low-density lipoprotein receptor–null (LDLR –/– ) mice and fed them a Western diet for 8 weeks. Mal1 –/– LDLR –/– mice had significantly reduced (36%) atherosclerosis in the ... Related articles - All 3 versions