HM Tang, JA French, RI Kuzniecky, O Devinsky… - Neuroscience …, 2011 - Elsevier Periodic transmeningeal administration of muscimol into the neocortical epileptogenic zone via a subdurally implanted device has been proposed for the treatment of intractable focal neocortical epilepsy. It is unknown whether such muscimol applications induce tolerance. The ... Related articles - All 2 versions
DE Rusyniak, DV Zaretsky, MV Zaretskaia… - Neuroscience …, 2011 - ncbi.nlm.nih.gov The medial preoptic area (mPOA) of the hypothalamus has long been thought to play an important role in both fever production and thermoregulation. Microinjections of prostaglandin E2 (PgE2) or the GABA(A) agonist muscimol into the mPOA cause similar increases in body ...
D Xu, B Karain, E Brantley… - Journal of Pharmacology and …, 2011 - ASPET Parkinson's disease (PD) is a movement disorder caused by the degeneration of dopamine (DA) neurons in the substantia nigra (SN). l-DOPA and direct DA agonists are the most common medications for PD. Compared with direct DA agonists, however, the DA precursor ... Related articles - All 3 versions
K Rea, M Roche… - The Journal of Pain, 2011 - Elsevier Evidence suggests that gamma-aminobutyric acid (GABA) signalling in the basolateral amygdala (BLA) is involved in pain, fear, and fear-conditioned analgesia (FCA). In this study, we investigated the effects of intra-BLA administration of the GABA A receptor agonist muscimol on the ... Related articles - All 4 versions
N Ludvig, HM Tang, NS Artan, P Mirowski… - Brain Research, 2011 - Elsevier Muscimol has potent antiepileptic efficacy after transmeningeal administration in animals. However, it is unknown whether this compound stops local neuronal firing at concentrations that prevent seizures. The purpose of this study was to test the hypothesis that epidurally ... All 3 versions