JS Brockenbrough, T Souquet… - Journal of Nuclear …, 2011 - Soc Nuclear Med We report the first, to our knowledge, findings describing the relationships between both static and dynamic analysis parameters of 3′-deoxy-3′- 18 F-fluorothymidine ( 18 F-FLT) PET and the expression of the proliferation marker Ki-67, and the protein expression and ...
L Wang, R Sun… - Antimicrobial Agents and …, 2011 - Am Soc Microbiol Mitochondrial thymidine kinase 2 (TK2) is a key enzyme in the salvage of pyrimidine deoxynucleosides needed for mitochondrial DNA synthesis. TK2 phosphorylates thymidine (dThd), deoxycytidine (dCyd), and many other antiviral pyrimidine nucleoside analogs. Zidovudine (AZT) is the ... Related articles - All 3 versions
T Shiota, W Lixin, M Takayama-Ito, I Iizuka… - Antiviral Research, 2011 - Elsevier Antiviral-resistant herpesvirus infection has become a great concern for immunocompromised patients. Herpes simplex virus type 1 (HSV-1) infections are treated with viral thymidine kinase (vTK)-associated drugs such as acyclovir (ACV), and most ACV-resistance (ACV r ) is due ... All 2 versions
T Radivoyevitch, B Munch-Petersen… - … and Nucleic Acids, 2011 - Taylor & Francis The mitochondrial enzyme thymidine kinase 2 (TK2) phosphorylates deoxythymidine (dT) and deoxycytidine (dC) to form dTMP and dCMP, which in cells rapidly become the negative-feedback end-products dTTP and dCTP. TK2 kinetic activity exhibits Hill coefficients of 0.5 ... Related articles - All 4 versions
C Di Cresce, R Figueredo, PJ Ferguson… - … of Pharmacology and …, 2011 - ASPET Page 1. JPET #183178 1 Title Page Title: Combining siRNAs Targeting Thymidylate Synthase and ThymidineKinase 1 or 2 Sensitizes Human Tumor Cells to 5FUdR and Pemetrexed* ... with Tween 20; TK, ThymidineKinase (general); TK1, cytosolic thymidinekinase 1; ... Related articles
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