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FG Smith, JE Fewell… - Clinical and Experimental …, 2011 - Wiley Online Library
... 2 Following exposure to a blood-borne exogenous pyrogen such as lipopolysaccharide (LPS),
cells of the immune system synthesize and secrete endogenous pyrogens, including interleukin
(IL)-1β, IL-6 and tumour necrosis factor-α, 3 which results in the production of cyclo ...
PA Ward - Shock, 2011 - journals.lww.com
... Although exogenous pyrogens such as LPS are well known to induce fever, it is unclear if
they are responsible for induction of the prefebrile variations in temperature patterns described
in this report and featuring patients with gram-negative bacteremia. ...
MS Oakley, N Gerald, TF McCutchan, L Aravind… - Trends in …, 2011 - Elsevier
... IL-6, as well as complement factor 5a (C5a) and prostaglandin E 2 (PGE 2 ) [7]. Phagocytic
monocytes in peripheral tissues have been shown to be important sources of these endogenous
pyrogens in response to the exogenous pyrogens derived from pathogenic organisms. ...
DJ Niven, C Leger, HT Stelfox… - Journal of Intensive …, 2011 - jic.sagepub.com
... In this model, the exogenous pyrogen (LPS) activates mononuclear phagocytic cells to produce
endo- genous pyrogenic cytokines such as those listed in Table 1.17 These molecules are
transported via the blood to circumventri- cular organs where they cross the blood-brain ...
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BN Alexander… - American Journal of Physiology- …, 2011 - Am Physiological Soc
... of pregnancy. The present experiments were carried out to determine the role of
endogenous glucocorticoids in mediating the altered core temperature (Tc) response
to exogenous pyrogen (ie, Escherichia coli LPS). For the ...
Related articles - All 3 versions

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