MJ Eddins, JG Marblestone… - Cell biochemistry and …, 2011 - Springer Abstract Progressive muscle wasting, also known as myopathy or muscle atrophy is a debilitating and life- threatening disorder. Myopathy is a pathological condition of many diseases including cancer, diabetes, COPD, and AIDS and is a natural consequence of inactivity and aging ( ... Related articles - All 3 versions
S Usui, Y Maejima, J Pain, C Hong… - Circulation …, 2011 - Am Heart Assoc Methods and Results: Expression of MAFbx in WT mice was significantly increased by TAC. TAC-induced increases in cardiac hypertrophy were significantly smaller in MAFbx KO than in WT mice. There was significantly less lung congestion and interstitial fibrosis in MAFbx ... Cited by 2 - Related articles - All 3 versions
[PDF] from uiowa.eduSD Kunkel, M Suneja, SM Ebert, KS Bongers… - Cell Metabolism, 2011 - Elsevier Skeletal muscle atrophy is a common and debilitating condition that lacks a pharmacologic therapy. To develop a potential therapy, we identified 63 mRNAs that were regulated by fasting in both human and mouse muscle, and 29 mRNAs that were regulated by both fasting ... Related articles - All 3 versions
DJ Glass - Phosphoinositide 3-kinase in Health and Disease, 2011 - Springer Abstract Activation of the PI3 kinase pathway can induce skeletal muscle hyper- trophy, defined as an increase in skeletal muscle mass. In mammals, skeletal muscle hypertrophy occurs as a result of an increase in the size, as opposed to the number, of pre-existing skeletal ... Cited by 11 - Related articles - All 5 versions
[HTML] from plos.orgCL Wu, SC Kandarian… - PloS one, 2011 - dx.plos.org Skeletal muscle atrophy is a debilitating condition associated with weakness, fatigue, and reduced functional capacity. Nuclear factor-kappaB (NF-κB) transcription factors play a critical role in atrophy. Knockout of genes encoding p50 or the NF-κB co-transactivator, Bcl-3, abolish ... Cited by 2 - Related articles - Cached - All 7 versions
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