F Li… - Science, 2011 - sciencemag.org CD40, a member of the tumor necrosis factor receptor (TNFR) superfamily, is expressed on antigen-presenting cells (APCs) and is essential for immune activation. Although agonistic CD40 antibodies have been developed for immunotherapy, their clinical efficacy has been ... Cited by 1
[PDF] from caltech.eduJ GroBer… - 2011 - writing.caltech.edu We study a citizen candidate entry model with private information about ideal points. We fully characterize the unique symmetric equilibrium of the entry game, and show that only relatively “extreme” citizen types enter the electoral competition as candidates, whereas more “ ... Related articles - View as HTML - All 3 versions
AV KRISHNAN… - Annual review of pharmacology and …, 2011 - cat.inist.fr Calcitriol, the hormonally active form of vitamin D, is being evaluated in clinical trials as an anti-cancer agent. Calcitriol exerts multiple anti-proliferative, pro-apoptotic, and pro-differentiating actions on various malignant cells and retards tumor growth in animal models of cancer. ... Cited by 6 - Related articles - All 2 versions
Y Zhang, CJ Ma, JM Wang, XJ Ji… - Journal of …, 2011 - Soc Leukocyte Biology ABSTRACT Tim-3 and PD-1 are powerful immunoinhibitory mole- cules involved in immune tolerance, autoimmune re- sponses, and antitumor or antiviral immune evasion. A current model for Tim-3 regulation during immune re- sponses suggests a divergent function, such that ...
C Garofalo, MC Manara, G Nicoletti, MT Marino… - Oncogene, 2011 - nature.com Identification of patient selection criteria and understanding of the potential mechanisms involved in the development of resistance are crucial for an appropriate and successful design of clinical trials with anti-insulin-like growth factor (IGF)-1R therapies. Few Ewing's sarcomas are ... Cited by 2 - Related articles - All 3 versions
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