B Ruffell… - Nature Medicine, 2011 - nature.com Tumors do not develop in spite of their 'host' but rather with the combined support of normal cells that comprise the tumor stroma, including fibroblasts and other niche-defining cells, vascular cells and various leukocyte populations. These cells participate in a maladaptive immune ... All 3 versions
[PDF] from wustl.eduSR Wilson, KA Gerhold, A Bifolck-Fisher… - Nature …, 2011 - nature.com Itch, the unpleasant sensation that evokes a desire to scratch, accompanies numerous skin and nervous system disorders. In many cases, pathological itch is insensitive to antihistamine treatment. Recent studies have identified members of the Mas-related G protein–coupled ... Cited by 2 - Related articles - All 4 versions
P Desai… - European Journal of Immunology, 2011 - Wiley Online Library The histamine H 4 receptor (H 4 R) has been implicated in numerous inflammatory functions. Here it is shown that the receptor can mediate cytokine production from mast cells. Histamine and an H 4 R agonist, JNJ 28610244, induced the production of IL-6 in mouse ... Related articles - All 2 versions
[HTML] from cjb.netP Sikand, X Dong… - The Journal of Neuroscience, 2011 - neuro.cjb.net Chronic itch accompanying many dermatological, neurological, and systemic diseases is unresponsive to antihistamines. Our knowledge of endogenous chemicals that evoke histamine-independent itch and their molecular targets is very limited. Recently it was demonstrated in behavioral ... Cited by 1 - Related articles - All 4 versions
FB Thoren, J Aurelius… - Nature Medicine, 2011 - nature.com Yang et al. 1 recently reported that mice with histamine deficiency due to genetic disruption of histidine decarboxylase (HDC) show impaired myeloid cell differentiation. The absence of histamine formation caused accumulation of immature myeloid cells (IMCs), which was ... All 3 versions