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RL Paquette, J Nicoll, M Chalukya, D Elashoff… - Cancer Genetics, 2011 - Elsevier
Clinical variables associated with ecotropic viral integration site 1 (EVI1) translocations were
evaluated in 42 consecutive chronic myeloid leukemia (CML) patients in myeloid blast crisis
(MBC). Translocations were confirmed with fluorescence in situ hybridization, and ...
RK Sachs, K Johnsson, P Hahnfeldt, J Luo, A Chen… - Cancer research, 2011 - AACR
Chronic myeloid leukemia (CML) is characterized by a specific chromosome translocation, and
its pathobiology is considered comparatively well understood. Thus, quantitative analysis of CML
and its progression to blast crisis may help elucidate general mechanisms of ...
Cited by 1 - Related articles - All 4 versions
K Sakai, Y Ishikawa, Y Mori, M Kobayashi… - International journal of …, 2011 - Springer
Abstract BCR-ABL kinase domain mutations were sequentially analyzed in a patient with chronic
myeloid leukemia (CML) who exhibited repeated B-lymphoid blast crisis (CML-BC) during treatment
with imatinib and dasatinib. We first identified five mutant BCR-ABL clones: Y253H, ...
Cited by 1 - Related articles - All 3 versions
C Matte-Martone, S Venkatesan… - The Journal of …, 2011 - Am Assoc Immnol
Graft-versus-leukemia (GVL) against chronic-phase chronic myelogenous leukemia
(CP-CML) is potent, but it is less efficacious against acute leukemias and blast-crisis chronic
myelogenous leukemia (BC-CML). The mechanisms underlying GVL resistance are ...
LF Peterson, E Mitrikeska, D Giannola, Y Lui… - Leukemia, 2011 - nature.com
Philadelphia chromosome positive chronic myeloid leukemia has a progressive course starting
in a benign phase and terminating in a blastic phase. In this study, we show that human homolog
double minute 2 (HDM2) inhibition, with MI-219—a novel compound, and consequently ...
All 4 versions

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