R Krencik, JP Weick, Y Liu, ZJ Zhang… - Nature Biotechnology, 2011 - nature.com Human pluripotent stem cells (hPSCs) have been differentiated efficiently to neuronal cell types. However, directed differentiation of hPSCs to astrocytes and astroglial subtypes remains elusive. In this study, hPSCs were directed to nearly uniform populations of immature ... Cited by 2 - Related articles - All 3 versions
HJ Joo, H Kim, SW Park, HJ Cho, HS Kim… - Blood, 2011 - ncbi.nlm.nih.gov Angiopoietin-1 (Ang1) plays a crucial role in vascular and hematopoietic development mainly through its cognate receptor Tie2. However, little is known about the precise role of Ang1 on embryonic stem cell (ESC) differentiation. Here, using COMP-Ang1 (soluble and potent ...
V Sebastiano, ML Maeder, JF Angstman… - STEM …, 2011 - Wiley Online Library Author contributions: VS: Collection and/or assembly of data, data analysis and interpretation, manuscript writing, final approval of manuscript; MLM: Collection and/or assembly of data, data analysis and interpretation, manuscript writing, final approval of manuscript; ...
M Pawlak… - Genes & Development, 2011 - genesdev.cshlp.org Induced pluripotent stem cells (iPSCs) are generated from somatic cells by the transduction of defined transcription factors, and this process involves dynamic changes in DNA methylation. While the reprogramming of somatic cells is accompanied by demethylation ... Related articles - All 2 versions
F Karanu… - US Patent 20,110,212,067, 2011 - freepatentsonline.com The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention provides methods of characterization of cells differentiated into cells expressing markers characteristic of the pancreatic endocrine lineage utilizing ... Cached