推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-33361733,021-34243363

chinasupport@letpub.com

登录 注册 新注册优惠

M Çalışkan, JX Chong, L Uricchio… - … molecular genetics, 2011 - Oxford Univ Press
Exome sequencing is a powerful tool for discovery of the Mendelian disease genes.
Previously, we reported a novel locus for autosomal recessive non-syndromic mental retardation
(NSMR) in a consanguineous family [Nolan, DK, Chen, P., Das, S., Ober, C. and ...
Cited by 9 - Related articles - All 5 versions
[HTML] from nih.govCCA Spencer, V Plagnol, A Strange… - … Molecular Genetics, 2011 - Oxford Univ Press
We performed a genome-wide association study (GWAS) in 1705 Parkinson's disease (PD) UK
patients and 5175 UK controls, the largest sample size so far for a PD GWAS. Replication was
attempted in an additional cohort of 1039 French PD cases and 1984 controls for the 27 ...
Cited by 8 - Related articles - All 7 versions
E Fossale, IS Seong, KR Coser… - … Molecular Genetics, 2011 - Oxford Univ Press
Huntington's disease (HD) involves marked early neurodegeneration in the striatum, whereas
the cerebellum is relatively spared despite the ubiquitous expression of full-length mutant
huntingtin, implying that inherent tissue-specific differences determine susceptibility to the ...
DG Hernandez, MA Nalls, JR Gibbs… - … molecular genetics, 2011 - Oxford Univ Press
Methylation at CpG sites is a critical epigenetic modification in mammals. Altered DNA methylation
has been suggested to be a central mechanism in development, some disease processes and
cellular senescence. Quantifying the extent and identity of epigenetic changes in the ...
Cited by 6 - Related articles - All 5 versions
A Singleton… - Human Molecular Genetics, 2011 - Oxford Univ Press
The dominant and sometimes competing theories for the aetiology of complex human disease
have been the common disease, common variant (CDCV) hypothesis, and the multiple rare variant
(MRV) hypothesis. With the advent of genome wide association studies and of second- ...

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海    网站备案号:沪ICP备10217908号-1    沪公网安备号:31010402006960 (网站)31010405000484 (蝌蝌APP)

增值电信业务经营许可证:沪B2-20211595    网络文化经营许可证:沪网文[2023]2004-152号

礼翰商务信息咨询(上海)有限公司      办公地址:上海市徐汇区漕溪北路88号圣爱大厦1803室