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JOURNAL OF MEDICINAL CHEMISTRY

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期刊名:   ISSN:   研究方向:   影响因子: -   SCI收录:
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JOURNAL OF MEDICINAL CHEMISTRY期刊基本信息Hello,您是该期刊的第291445位访客


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期刊名字JOURNAL OF MEDICINAL CHEMISTRYJOURNAL OF MEDICINAL CHEMISTRY

J. Med. Chem.
(此期刊被最新的JCR期刊SCIE收录)

LetPub评分
8.4
72人评分
我要评分

声誉
9.0

影响力
7.8

速度
9.4

期刊ISSN0022-2623
微信扫码收藏此期刊
E-ISSN1520-4804
2023-2024最新影响因子
(数据来源于搜索引擎)
6.8 点击查看影响因子趋势图
实时影响因子 截止2024年3月26日:6.69
2023-2024自引率10.30%点击查看自引率趋势图
五年影响因子7.1
JCI期刊引文指标 2.04
h-index 240
CiteScore
2024年最新版
CiteScoreSJRSNIPCiteScore排名
12.801.9861.594
学科分区排名百分位
大类:Pharmacology, Toxicology and Pharmaceutics
小类:Drug Discovery
Q113 / 157
大类:Pharmacology, Toxicology and Pharmaceutics
小类:Molecular Medicine
Q124 / 178

期刊简介
The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.

Some specific areas that are appropriate include the following:
Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools.
Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that do not utilize novel chemical or biological approaches or do not add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication.
Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds.
Molecular biological studies (e.g., site-directed mutagenesis) of macromolecular targets that lead to an improved understanding of molecular recognition.
Computational studies that provide fresh insight into the SAR of compound series that are of current general interest or analysis of other available data that subsequently advance medicinal chemistry knowledge.
Substantially novel computational chemistry methods with demonstrated value for the identification, optimization, or target interaction analysis of bioactive molecules.
Effect of molecular structure on the distribution, pharmacokinetics, and metabolic transformation of biologically active compounds. This may include design, synthesis, and evaluation of novel types of prodrugs.
Novel methodology with broad application to medicinal chemistry, but only if the methods have been tested on relevant molecules.
期刊官方网站https://pubs.acs.org/journal/jmcmar
期刊投稿网址https://acs.manuscriptcentral.com/acs
期刊语言要求经LetPub语言功底雄厚的美籍native English speaker精心编辑的稿件,不仅能满足JOURNAL OF MEDICINAL CHEMISTRY的语言要求,还能让JOURNAL OF MEDICINAL CHEMISTRY编辑和审稿人得到更好的审稿体验,让稿件最大限度地被JOURNAL OF MEDICINAL CHEMISTRY编辑和审稿人充分理解和公正评估。LetPub的专业SCI论文编辑服务(包括SCI论文英语润色同行资深专家修改润色SCI论文专业翻译SCI论文格式排版专业学术制图等)帮助作者准备稿件,已助力全球15万+作者顺利发表论文。部分发表范例可查看:服务好评(2篇) 论文致谢
提交文稿
是否OA开放访问Transformative (TJ转换期刊是订阅式/混合期刊,但是正在积极转为完全开放获取期刊。查看ACS说明。)
通讯方式AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036
出版商American Chemical Society
涉及的研究方向医学-医药化学
出版国家或地区UNITED STATES
出版语言English
出版周期Biweekly
出版年份1959
年文章数 922点击查看年文章数趋势图
Gold OA文章占比13.77%
研究类文章占比:
文章 ÷(文章 + 综述)
98.81%
WOS期刊SCI分区
2023-2024年最新版
WOS分区等级:1区

按JIF指标学科分区收录子集JIF分区JIF排名JIF百分位
学科:CHEMISTRY, MEDICINALSCIEQ14/72
按JCI指标学科分区收录子集JCI分区JCI排名JCI百分位
学科:CHEMISTRY, MEDICINALSCIEQ11/72
中国科学院《国际期刊预警
名单(试行)》名单
2024年02月发布的2024版:不在预警名单中

2023年01月发布的2023版:不在预警名单中

2021年12月发布的2021版:不在预警名单中

2020年12月发布的2020版:不在预警名单中
中国科学院SCI期刊分区
2023年12月最新升级版
点击查看中国科学院SCI期刊分区趋势图
大类学科小类学科Top期刊综述期刊
医学 4区1区3区
CHEMISTRY, MEDICINAL
药物化学
4区2区1区
中国科学院SCI期刊分区
2022年12月升级版
大类学科小类学科Top期刊综述期刊
医学 2区1区1区
CHEMISTRY, MEDICINAL
药物化学
2区4区1区
中国科学院SCI期刊分区
2021年12月旧的升级版
大类学科小类学科Top期刊综述期刊
医学 3区1区4区
CHEMISTRY, MEDICINAL
药物化学
2区1区1区
SCI期刊收录coverage Science Citation Index Expanded (SCIE) (2020年1月,原SCI撤销合并入SCIE,统称SCIE)
Scopus (CiteScore)
PubMed Central (PMC)链接http://www.ncbi.nlm.nih.gov/nlmcatalog?term=0022-2623%5BISSN%5D
平均审稿速度网友分享经验:
平均2.1个月
平均录用比例网友分享经验:
较难
LetPub助力发表经LetPub编辑的稿件平均录用比例是未经润色的稿件的1.5倍,平均审稿时间缩短40%。众多作者在使用LetPub的专业SCI论文编辑服务(包括SCI论文英语润色同行资深专家修改润色SCI论文专业翻译SCI论文格式排版专业学术制图等)后论文在JOURNAL OF MEDICINAL CHEMISTRY顺利发表。
快看看作者怎么说吧:服务好评 论文致谢
收稿范围期刊官网数据:
期刊收录研究方向:
药理工具的新型生物活性化合物、诊断剂或标记配体的设计、合成和生物学评估
分子修饰以增进对构效关系(SAR)的认知。(没有创新性的化学或生物学方法或没有对SAR进行深入分析的常规工作通常将不予出版)
有关配体和靶标的结构生物学研究(X射线,NMR等),以探究生物活性化合物作用下的分子识别过程
大分子靶标的分子生物学研究(例如定点诱变)以增进对分子识别的理解
具有最新见解的化合物SAR计算研究,这些化合物当前具有普遍价值,或者可用于分析其他有用数据,从而进一步提高对药物化学的认知
新颖的计算化学方法,对于生物活性分子的鉴定、优化或标靶相互作用分析具有证明价值
分子结构对生物活性化合物的分布、药代动力学和代谢转化的影响。这可能包括新型药物前体的设计、合成和评估
可广泛应用于药物化学的新方法,且该方法已在相关分子上进行测试
收录体裁期刊官网数据:
Articles
Brief Articles
Perspectives
Drug Annotations
Viewpoint
Featured Articles
期刊常用信息链接
同领域相关期刊 JOURNAL OF MEDICINAL CHEMISTRY期刊近年CiteScore指标趋势图
该杂志的自引率趋势图 JOURNAL OF MEDICINAL CHEMISTRY中国科学院SCI期刊分区趋势图
该杂志的年文章数趋势图 同领域作者分享投稿经验
JOURNAL OF MEDICINAL CHEMISTRY上中国学者近期发表的论文  
  • 同领域相关期刊
  • 期刊CiteScore趋势图
  • 期刊自引率趋势图
  • 中国科学院分区趋势图
  • 年文章数趋势图
  • 该期刊中国学者近期发文
  • 中国科学院分区相关期刊
  • 同类著名期刊名称 h-index CiteScore
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY13511.70
    Marine Drugs849.60
    MINI-REVIEWS IN MEDICINAL CHEMISTRY797.80
    CURRENT TOPICS IN MEDICINAL CHEMISTRY1046.40
    MEDICINAL CHEMISTRY RESEARCH384.70
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS1335.70
    Medicinal Chemistry394.30
    NATURAL PRODUCT RESEARCH425.10
    Records of Natural Products243.10
    Letters in Drug Design & Discovery281.80
    中国科学院SCI期刊分区同大类学科的热搜期刊 浏览次数
    MEDICINE660215
    BIOMATERIALS555470
    BIOMEDICINE & PHARMACOTHERAPY533660
    Frontiers in Pharmacology501462
    Journal of Materials Chemistry B492896
    Frontiers in Immunology477337
    COMPUTERS IN BIOLOGY AND MEDICINE454164
    JOURNAL OF ETHNOPHARMACOLOGY452204
    COLLOIDS AND SURFACES B-BIOINTERFACES431122
    Frontiers in Oncology425269
  •  

    JOURNAL OF MEDICINAL CHEMISTRY JOURNAL OF MEDICINAL CHEMISTRY
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  • 中国学者近期发表的论文
    1.Design, Synthesis, and Antitumor Activity of Potent and Selective EGFR L858R/T790M Inhibitors and Identification of a Combination Therapy to Overcome Acquired Resistance in Models of Non-small- cell Lung Cancer

    Author: Pei, Junping; Wang, Guan; Wang, Aoxue; Wu, Chengyong; Pan, Xiaoli; Shuai, Wen; Bu, Faqian; Zhu, Yumeng; Wang, Yuxi; Ouyang, Liang; Li, Weimin
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. , Issue , pp. -. DOI: 10.1021/acs.jmedchem.3c00027
        PubMed      DOI
    2.Discovery of Pyridinone Derivatives as Potent, Selective, and Orally Bioavailable Adenosine A2A Receptor Antagonists for Cancer Immunotherapy

    Author: Zhu, Chenyu; Ze, Shuyin; Zhou, Ronghui; Yang, Xinyu; Wang, Haojie; Chai, Xiaolei; Fang, Meimiao; Liu, Mingyao; Wang, Yonghui; Lu, Weiqiang; Xie, Qiong
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 4734-4754. DOI: 10.1021/acs.jmedchem.2c018604734J
        PubMed      DOI
    3.Targeting Receptor-Interacting Protein Kinase 1 by Novel Benzothiazole Derivatives: Treatment of Acute Lung Injury through the Necroptosis Pathway

    Author: Zhang, Xinqi; Han, Qianyu; Hou, Ruilin; Xu, Lijuan; Zhang, Wannian; Xing, Chengguo; Xue, Lei; Zhuang, Chunlin
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 5261-5278. DOI: 10.1021/acs.jmedchem.3c00197
        PubMed      DOI
    4.Application and Study of ROCK Inhibitors in Pulmonary Fibrosis: Recent Developments and Future Perspectives

    Author: Xie, Yuting; Yue, Lin; Shi, Yaojie; Su, Xingping; Gan, Cailing; Liu, Hongyao; Xue, Taixiong; Ye, Tinghong
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 4342-4360. DOI: 10.1021/acs.jmedchem.2c01753
        PubMed      DOI
    5.Development of Son of Sevenless Homologue 1 (SOS1) Modulators To Treat Cancers by Regulating RAS Signaling

    Author: Luo, Guangmei; Wang, Bingrui; Hou, Qiangqiang; Wu, Xiaoxing
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 4324-4341. DOI: 10.1021/acs.jmedchem.2c01729
        PubMed      DOI
    6.Unsymmetrical Phosphodiesters as GPR84 Antagonists with High Blood Exposure for the Treatment of Lung Inflammation

    Author: Li, Shao-Xian; Wang, Si-Wei; Chen, Lin-Hai; Zhang, Qing; Lu, Dan; Chen, Jing; Fang, You-Chen; Gu, Min; Xie, Xin; Nan, Fa-Jun
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 8, pp. 5820-5838. DOI: 10.1021/acs.jmedchem.3c00053
        PubMed      DOI
    7.Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1

    Author: Gallego, Rebecca A.; Bernier, Louise; Chen, Hui; Cho-Schultz, Sujin; Chung, Loanne; Collins, Michael; Del Bel, Matthew; Elleraas, Jeff; Jones, Cinthia Costa; Cronin, Ciaran N.; Edwards, Martin; Fang, Xu; Fisher, Timothy; He, Mingying; Hoffman, Jacqui; Huo, Ruiduan; Jalaie, Mehran; Johnson, Eric; Johnson, Ted W.; Kania, Robert S.; Kraus, Manfred; Lafontaine, Jennifer; Le, Phuong; Liu, Tongnan; Maestre, Michael; Matthews, Jean; McTigue, Michele; Miller, Nichol; Mu, Qiming; Qin, Xulong; Ren, Shijian; Richardson, Paul; Rohner, Allison; Sach, Neal; Shao, Li; Smith, Graham; Su, Ruirui; Sun, Bin; Timofeevski, Sergei; Tran, Phuong; Wang, Shuiwang; Wang, Wei; Zhou, Ru; Zhu, Jinjiang; Nair, Sajiv K.
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 7, pp. 4888-4909. DOI: 10.1021/acs.jmedchem.2c02038
        PubMed      DOI
    8.Exploration of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Bispecific Inhibitors Based on the Moiety of Fedratinib for Treatment of Both Hematologic Malignancies and Solid Cancers

    Author: Qiu, Qianqian; Chi, Fanglian; Zhou, Daoguang; Xie, Zhancheng; Liu, Yunxiao; Wu, Hanyu; Yin, Ziyu; Shi, Wei; Qian, Hai
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. , Issue , pp. -. DOI: 10.1021/acs.jmedchem.3c00036
        PubMed      DOI
    9.Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects

    Author: Peng, Xiaopeng; Ren, Yichang; Pan, Wanyi; Liu, Jin; Chen, Jianjun
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 1, pp. 627-640. DOI: 10.1021/acs.jmedchem.2c01566
        PubMed      DOI
    10.Structural and Functional Landscape of FAD-Dependent Histone Lysine Demethylases for New Drug Discovery

    Author: Song, Yihui; Wang, Shu; Yu, Bin
    Journal: JOURNAL OF MEDICINAL CHEMISTRY. 2023; Vol. 66, Issue 1, pp. 71-94. DOI: 10.1021/acs.jmedchem.2c01324
        PubMed      DOI
  • 同大类学科的其他著名期刊名称 h-index CiteScore
    CA-A CANCER JOURNAL FOR CLINICIANS144873.20
    NATURE REVIEWS DRUG DISCOVERY289137.40
    LANCET700148.10
    NEW ENGLAND JOURNAL OF MEDICINE933145.40
    BMJ-British Medical Journal019.90
    BMJ-British Medical Journal019.90
    Nature Reviews Clinical Oncology12799.40
    Nature Reviews Disease Primers4876.70
    NATURE REVIEWS CANCER396111.90
    NATURE REVIEWS IMMUNOLOGY35193.40
    同分区等级的其他期刊名称 h-index CiteScore
    CA-A CANCER JOURNAL FOR CLINICIANS144873.20
    NATURE REVIEWS DRUG DISCOVERY289137.40
    LANCET700148.10
    NEW ENGLAND JOURNAL OF MEDICINE933145.40
    BMJ-British Medical Journal019.90
    BMJ-British Medical Journal019.90
    NATURE REVIEWS MOLECULAR CELL BIOLOGY386173.60
    Nature Reviews Clinical Oncology12799.40
    Nature Reviews Materials61119.40
    Nature Reviews Disease Primers4876.70
以上SCI期刊相关数据和信息来源于网络,仅供参考。
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同领域作者分享投稿经验:共72


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